The rush to mass vaccinate the world with genetic vaccines in 2021 has been met with controversy and concerns about safety and efficacy. One area of concern is the vaccination of pregnant women, as there has been limited preclinical and clinical testing during gestation. Now, a recent rat study by Erdogan et al has shed light on potential neurodevelopmental problems associated with the Pfizer BNT162b2 vaccine.
The study found that pregnant rats injected with the Pfizer vaccine had male offspring that exhibited neurodegenerative changes and impaired behaviors on standardized testing. These effects were particularly pronounced in males, with outcomes including autism-like behaviors, reduced neuronal counts, and impaired motor performance. The study also showed that the vaccine impacted the Wnt pathway, which is crucial for the development and maturation of the central nervous system, as well as brain-derived neurotrophic factor (BDNF) levels.
These findings raise concerns about the potential neurodevelopmental implications of the Pfizer vaccine in humans, especially in male offspring. The study aligns with existing literature on the roles of the Wnt pathway and BDNF signaling in neurodevelopmental disorders. However, it's important to note that this study was conducted on rats, and further research is needed to determine if similar effects occur in humans.
The implications of this study are significant, as it highlights the need for more thorough preclinical and clinical testing of vaccines, especially when it comes to pregnant women. The American College of Obstetrics and Gynecology (ACOG) broke from its conservative stance on novel products and endorsed the Pfizer vaccine for pregnant women without sufficient evidence of safety or efficacy.
